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See Pediatric Use under Cautions

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms. Risk of suicidality; importance of patients, family, and caregivers being alert to and immediately reporting emergence of suicidality, worsening depression, or unusual changes in behavior, especially during the first few months of therapy or during periods of dosage adjustment. a d h i j k l FDA recommends providing written patient information medication guide explaining risks of suicidality each time the drug is dispensed. zyrtec

Sinequan uses

Initial dose: 75 mg per day in 1 to 3 divided doses. Depression and certain other psychiatric disorders are themselves associated with an increased risk of suicide. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sinequan concentrate while you are pregnant. Sinequan concentrate is found in breast milk. Do not breast-feed while taking Sinequan concentrate.

CYP3A4 as minor pathways

Pons G, Greene SL, Reed CE, Schroeter AL. Double-blind crossover study comparing doxepin with diphenhydramine for the treatment of chronic urticaria. J Am Acad Dermatol. Therefore, before using doxepin, report all medications you are currently using to your doctor or pharmacist. Debe esperar un mínimo de 5 semanas después de dejar de usar fluoxetine Prozac antes que pueda tome doxepin. Glaucoma or urinary retention.

Sinequan adult dosage

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. If you take it only once a day, take it at to reduce daytime sleepiness. The dosage is based on your medical condition and response to treatment. Sinequan concentrate may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Sinequan concentrate with caution.



QT prolongation see above

This medication has been prescribed for your current condition only. Do not use it later for other conditions unless directed by your doctor. A different medication may be necessary in those cases. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sinequan while you are pregnant. Sinequan is found in breast milk. Do not breast-feed while taking Sinequan. Watson Laboratories, Inc. Doxepin hydrochloride capsule prescribing information. Corona, CA; 2005 May. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. If you miss a dose, take it as soon as you remember if it is still near and you have trouble falling asleep. No se conoce si doxepin causará daño al bebé nonato. Dígale a su médico si usted está embarazada o planea quedar embarazada. Sinequan is virtually devoid of euphoria as a side effect. Characteristic of this type of compound, Sinequan has not been demonstrated to produce the physical tolerance or psychological dependence associated with addictive compounds. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of Sinequan or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Sinequan is not approved for use in pediatric patients. Sutherland DL, Remillard AJ, Haight KR et al. The influence of cimetidine versus ranitidine on doxepin pharmacokinetics. Eur J Clin Pharmacol. Other medications can affect the removal of from your body, thereby affecting how doxepin works. Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses or planned surgery. No use doxepin si usted ha usado un inhibidor de MAO en los últimos 14 días. Una interacción peligrosa de medicamentos puede ocurrir. Los inhibidores de la MAO incluyen isocarboxazid, linezolid, inyección de azul de metileno, phenelzine, rasagiline, selegiline, tranylcypromine, y otros.



Sinequan consumer information

If your symptoms do not improve or if they become worse, check with your doctor. Individualize dosage carefully according to individual requirements and response. Possible exacerbation of psychosis in patients with schizophrenia; decrease dosage or administer an antipsychotic agent concomitantly. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. This information should not be used to decide whether or not to take Sinequan concentrate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Sinequan concentrate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Sinequan concentrate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Sinequan concentrate. However, the study could only point to an association between long-term or high-dose use of these drugs and a higher risk of dementia, it could not prove cause-and-effect. You should not take doxepin if you have glaucoma or problems with urination. Do not use if you are allergic to doxepin or to similar antidepressants. Carefully consider these findings when assessing potential benefits and risks of doxepin in a child or adolescent for any clinical use. a g h i j k l See Worsening of Depression and Suicidality Risk under Cautions. methimazole



What other drugs will affect sinequan

Food and Drug Administration. FDA news: FDA proposes new warnings about suicidal thinking, behavior in young adults who take antidepressant medications. Rockville, MD; 2007 May 2. From the FDA web site. The use of Sinequan in children under 12 years of age is not recommended because safe conditions for its use have not been established. How should I take doxepin Sinequan Sinequan? Call your doctor for medical advice about side effects. Some MEDICINES MAY INTERACT with Sinequan. Some MEDICINES MAY INTERACT with Sinequan concentrate. AHFS drug information 2007. McEvoy GK, ed. Doxepin hydrochloride. This medication may not work right away. You may see some benefit within a week. However, it may take up to 3 weeks before you feel the full effect. Drowsiness or may occur. If either of these effects persist or worsen, tell your doctor or promptly. Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details. Read the Medication Guide that comes with you or your family member's antidepressant medicine. This Medication Guide is only about the risk of suicidal thoughts and actions with antidepressant medicines. price coversyl 500 mg coversyl



How should i take sinequan

Prescribe in smallest quantity consistent with good patient management to reduce risk of overdosage. Goldsobel AB, Rohr AS, Siegel SC et al. Efficacy of doxepin in the treatment of chronic idiopathic urticaria. J Allergy Clin Immunol. Gastrointestinal: Nausea, vomiting, indigestion, taste disturbances, diarrhea, anorexia, and aphthous stomatitis have been reported. For most patients with illness of mild to moderate severity, a starting daily dose of 75 mg is recommended. Dosage may subsequently be increased or decreased at appropriate intervals and according to individual response. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Sinequan concentrate must be diluted before taking. Dilute Sinequan concentrate in 4 oz 120 mL of water, milk, or fruit juice. Sinequan included sufficient numbers of subjects aged 65 and over to define a difference in response from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. This information should not be used to decide whether or not to take Sinequan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Sinequan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Sinequan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Sinequan. What should I discuss with my healthcare provider before taking Sinequan doxepinSinequan? MAO inhibitors generally is contraindicated in patients receiving TCAs. a c k l See MAO Inhibitors under Interactions. Use Sinequan concentrate as directed by your doctor. Check the label on the medicine for exact dosing instructions. La ausencia en éste de una advertencia para una droga o combinación de drogas no debe, de ninguna forma, interpretarse como que la droga o la combinación de drogas sean seguras, efectivas, o apropiadas para cualquier paciente. Multum no se responsabiliza por ningún aspecto del cuidado médico que reciba con la ayuda de la información que proviene de Multum. La información incluida aquí no se ha creado con la intención de cubrir todos los usos posibles, instrucciones, precauciones, advertencias, interacciones con otras drogas, reacciones alérgicas, o efectos secundarios. Si usted tiene alguna pregunta acerca de las drogas que está tomando, consulte con su médico, enfermera, o farmacéutico. Other drugs may interact with doxepin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Where can I get more information? salbutamol to order



How to use sinequan

It may take 2 to 3 weeks before your depression symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Low levels of or in the may also increase your risk of QT prolongation. Some of the side effects that can occur with doxepin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. What should I avoid while taking doxepin Sinequan Sinequan? Take Sinequan by mouth with or without food. FDA warns that a greater risk of suicidal thinking or behavior suicidality occurred during first few months of antidepressant treatment 4% compared with placebo 2% in children and adolescents with major depressive disorder, OCD, or other psychiatric disorders based on pooled analyses of 24 short-term, placebo-controlled trials of 9 antidepressant drugs SSRIs and others. See Worsening of Depression and Suicidality Risk and Pediatric Use under Cautions. Usually, is temporary and requires only for a short time. Food and Drug Administration. Revisions to medication guide: antidepressant medicines, depression and other serious mental illnesses and suicidal thoughts or actions. Rockville, MD; 2007 May 2. From the FDA web site. Check with your doctor before you drink alcohol or use medicines that may cause drowsiness eg, sleep aids, muscle relaxers while you are using Sinequan; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. Tell your doctor or dentist that you take Sinequan before you receive any medical or dental care, emergency care, or surgery. Do not use doxepin if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Doxepin puede perjudicar su pensamiento o reacciones. Tenga cuidado si usted conduce un vehículo o tenga que hacer algo que demande se mantenga alerta. No suicides occurred in any of the pediatric trials. There were suicides in the adult trials, but the number was not sufficient to reach any conclusion about drug effect on suicide. Sinequan comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Sinequan refilled. Antidepressant medicines can interact with other medicines. Know all of the medicines that you or your family member takes. Keep a list of all medicines to show the healthcare provider. Do not start new medicines without first checking with your healthcare provider.



Common side effects of sinequan

It may help improve mood and feelings of well-being, relieve and tension, help you better, and increase your energy level. Antes de tomar doxepin, dígale a su médico si usted ha usado un antidepresivo "SSRI" en las últimas 5 semanas, como citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, o sertraline. Monitor for possible worsening of depression, suicidality, or unusual changes in behavior, especially at the beginning of therapy or during periods of dosage adjustments. a h i j k See Worsening of Depression and Suicidality Risk under Cautions. Busque atención médica de emergencia si tiene síntomas de una reacción alérgica: ronchas; dificultad para respirar; hinchazón de la cara, labios, lengua, o la garganta. Gray, director of the geriatric pharmacy program at the University of Washington's School of Pharmacy. Do not give this medicine to anyone under 18 years old without the advice of a doctor. Doxepin is not approved for use in children. Mechanism of action in the management of depressive and anxiety disorders is unknown but may involve inhibition of reuptake of norepinephrine. Doxepin may also be used for purposes not listed in this medication guide. What is the most important information I should know about Sinequan doxepinSinequan? indomethacin buy online visa canada



Sinequan side effects

Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. 2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have or have a family history of bipolar illness also called manic-depressive illness or suicidal thoughts or actions. 3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member? What other drugs will affect doxepin Sinequan Sinequan? Importance of informing patients of other important precautionary information. a k l See Cautions. See General under Dosage and Administration. When administered as a single daily dose, the maximum daily dose recommended is 150 mg. a k l Commercially available 150-mg capsules of doxepin are intended for maintenance therapy only and are not recommended for initial therapy. purchase quinine online mastercard canada quinine



Where can I get more information?

What should I discuss with my healthcare provider before taking doxepin Sinequan? Since overdosage is often deliberate, patients may attempt suicide by other means during the recovery phase. Psychiatric referral may be appropriate. Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with Sinequan and should counsel them in its appropriate use. A patient Medication Guide about "Antidepressant Medicines, Depression and other Serious Mental Illness, and Suicidal Thoughts or Actions" is available for Sinequan. The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication Guide and should assist them in understanding its contents. Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have. The complete text of the Medication Guide is reprinted at the end of this document. Doxepin puede también usarse para fines no mencionados en esta guía del medicamento. Peak plasma concentrations usually occur within 2 hours after oral administration. stromectol



Glaucoma or urinary retention

Risk of concomitant use with alcohol. Therefore, -feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Extensively metabolized in the liver by various CYP isoenzymes principally CYP2D6; also CYP1A2, CYP3A4; undergoes demethylation to pharmacologically active metabolite, N-desmethyldoxepin. a b k m p q Poor metabolizers of CYP2D6 metabolize the drug more slowly than normal metabolizers. Sinequan concentrate is to be used only by the patient for whom it is prescribed. Do not share it with other people. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. This medication guide provides information about the use of doxepin Sinequan or other generic names to treat depression or anxiety. Silenor is another brand of doxepin that is not covered in this medication guide. Rarely, after taking this drug, people have gotten out of bed and driven vehicles while not fully awake "-driving". Cimetidine has been reported to produce clinically significant fluctuations in steady-state serum concentrations of various tricyclic antidepressants. Ormerod AD. Urticaria: recognition, causes and treatment. Drugs. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; abnormal movements; aggressive or bizarre behavior; agitation; anxiety; chest pain; difficulty speaking and swallowing; disorientation; eye pain; fainting; fast, slow, or irregular heartbeat; hair loss; hallucinations; hostility; irritability; loss of balance; mood swings; nervousness or restlessness; panic attacks; ringing in the ears; seizures; shakiness; sore throat or fever; trouble sleeping; twitching of the face or tongue; unusual bleeding or bruising; yellowing of the skin or eyes. One way to fight anemia is to eat more iron-rich foods, like dark green leafy vegetables, beans, sweet potatoes, and meat. Or you can take an iron supplement. Other options are to get a blood transfusion or take medicine that helps your body make more red blood cells.



Gray offered similar advice

Doxepin may also be used for purposes not listed in this medication guide. Follow your doctor's instructions carefully. Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York City. He was not involved in the new study. Clinical experience has shown that Sinequan is safe and well tolerated even in the elderly patient. Owing to lack of clinical experience in the pediatric population, Sinequan is not recommended for use in children under 12 years of age. See Boxed Warning and also see Pediatric Use under Cautions. What should I discuss with my healthcare provider before taking doxepin Sinequan Sinequan? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Doxepin is a tricyclic antidepressant. Doxepin affects chemicals in the brain that may become unbalanced. For most patients with illness of mild to moderate severity, a starting daily dose of 75 mg doxepin is recommended. UU. sea apropiado, a menos que se mencione específicamente lo cual. La información de Multum sobre drogas no sanciona drogas, ni diagnóstica al paciente o recomienda terapia. Sinequan is contraindicated in individuals who have shown hypersensitivity to the drug. Possibility of cross sensitivity with other dibenzoxepines should be kept in mind. Serious side effects and even death have been reported following the concomitant use of certain drugs with MAO inhibitors. Therefore, MAO inhibitors should be discontinued at least two weeks prior to the cautious initiation of therapy with Sinequan. The exact length of time may vary and is dependent upon the particular MAO inhibitor being used, the length of time it has been administered, and the dosage involved. Allergic: Skin rash, edema, photosensitization, and pruritus have occasionally occurred. This drug may make you drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid beverages. Sinequan for 25 years. Started out with 25mg and increased dosage through the years to 150mg one capsule 2 hours before bed time. I was prescriped this drug by an orthopedic surgeon for lower back pain. I have not gained any weight as a result of it's usage all these years and it simple gave me my life back. cheap ranitidine order shop



What should i avoid while taking sinequan

Before taking doxepin, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, or sertraline. Cuál es la información más importante que debo saber sobre doxepin Sinequan? Doxepin may also be used for purposes not listed in this medication guide. What is the most important information I should know about doxepin Sinequan? Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. Otras drogas pueden interactuar con doxepin, incluyendo medicinas que se obtienen con o sin receta, vitaminas, y productos herbarios. No todas las interacciones posibles aparecen en esta guía del medicamento. Dígale a cada uno de sus proveedores de salud acerca de todas las medicinas que usted esté usando ahora, y cualquier medicina que usted comience o deje de usar. Store Sinequan concentrate at room temperature, between 68 and 77 degrees F 20 and 25 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Sinequan concentrate out of the reach of children and away from pets. Families and caregivers of patients being treated with antidepressants for major depressive disorder or other indications, both psychiatric and nonpsychiatric, should be alerted about the need to monitor patients for the emergence of agitation, irritability, unusual changes in behavior, and the other symptoms described above, as well as the emergence of suicidality, and to report such symptoms immediately to health care providers Such monitoring should include daily observation by families and caregivers. Prescriptions for Sinequan should be written for the smallest quantity of tablets consistent with good patient management, in order to reduce the risk of overdose. This is used to treat problems . It may help you stay asleep longer and reduce the number of times you awaken during the night. OCD, or non-OCD anxiety disorders suggests that the benefits of antidepressant therapy in treating these conditions may outweigh the risks of suicidal behavior or suicidal ideation. g No suicides occurred in these pediatric trials. See Specific Drugs under Interactions. QT prolongation see above. Concomitant use of tricyclic antidepressants with drugs that can inhibit cytochrome P450 2D6 may require lower doses than usually prescribed for either the tricyclic antidepressant or the other drug. Furthermore, whenever one of these other drugs is withdrawn from co-therapy, an increased dose of tricyclic antidepressant may be required. It is desirable to monitor TCA plasma levels whenever a TCA is going to be co-administered with another drug known to be an inhibitor of P450 2D6. Doxepin es un antidepresivo tricíclico que afecta a los químicos en su cerebro que pueden estar desequilibrados. fril.info propecia



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List of sinequan side effects


Maximum 300 mg daily

If you have any questions about Sinequan concentrate, please talk with your doctor, pharmacist, or other health care provider. Dosage is based on your medical condition, age, and response to therapy. Do not take more than 6 milligrams per day. The extent of interaction depends on the variability of effect on CYP2D6. The clinical significance of this interaction with doxepin has not been systematically evaluated. Consult your doctor before breast-feeding. Children, teenagers, and young adults who take Sinequan concentrate may be at increased risk for suicidal thoughts or actions. Watch all patients who take Sinequan concentrate closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur. generic dipyridamole buy now shop

What is sinequan

In rare instances, hemoperfusion may be beneficial in acute refractory cardiovascular instability in patients with acute toxicity. However, hemodialysis, peritoneal dialysis, exchange transfusions, and forced diuresis generally have been reported as ineffective in tricyclic antidepressant poisoning. Select dosage at the lower end of recommended range since decreased hepatic, renal, or cardiac function and concomitant illness and medications are more frequent; increase dosage more gradually and monitor closely. a k l May administer before bedtime. a See Geriatric Use under Cautions. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. protopic-ointment

Sinequan brand names

Sinequan is to be used only by the patient for whom it is prescribed. Do not share it with other people. Possibly severe withdrawal reactions; avoid abrupt discontinuance of therapy and taper dosage gradually. All patients suspected of tricyclic antidepressant overdose should receive gastrointestinal decontamination. This should include large volume gastric lavage followed by activated charcoal. If consciousness is impaired, the airway should be secured prior to lavage. Emesis is contraindicated. Bridge JA, Iyengar S, Salary CB. Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. JAMA. order now generic atorvastatin usa

Before taking sinequan

Sinequan is contraindicated in patients with glaucoma or a tendency to urinary retention. These disorders should be ruled out, particularly in older patients. Reproduction studies have been performed in rats, rabbits, monkeys and dogs and there was no evidence of harm to the animal fetus. The relevance to humans is not known. Since there is no experience in pregnant women who have received this drug, safety in pregnancy has not been established. There has been a report of apnea and drowsiness occurring in a nursing infant whose mother was taking Sinequan. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company.

The total doxepin dose should not exceed 6 mg per day. Deaths may occur from overdosage with this class of drugs. Multiple drug ingestion including alcohol is common in deliberate tricyclic antidepressant overdose. As the management is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity develop rapidly after tricyclic antidepressant overdose; therefore, hospital monitoring is required as soon as possible. Cardiovascular: Cardiovascular effects including hypotension, hypertension, and tachycardia have been reported occasionally.

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